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In vivo function of VDR in gene expression-VDR knock-out mice

โœ Scribed by Shigeaki Kato; Ken-ichi Takeyama; Sachiko Kitanaka; Akiko Murayama; Keisuke Sekine; Tatsuya Yoshizawa


Book ID
117669161
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
138 KB
Volume
69
Category
Article
ISSN
0960-0760

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The vitamin D receptor (VDR) is a nuclear receptor that mediates the effect of the active metabolite of vitamin D3, the 1,25-dihydroxyvitamin D3 (1,25-(OH)2D3). To investigate the potential role of this hormone in the peripheral nervous system, we have studied the VDR expression in Schwann cells. Th