## Abstract Survivin, a novel member of the inhibitor of apoptosis protein (IAP) family, reduces the susceptibility of tumor cells to proapoptotic stimuli, thereby promoting tumor cell survival during tumor progression and treatment with anticancer drugs. Recently, we identified 2 novel alternative
β¦ LIBER β¦
In vivo expression patterns of survivin and its splicing variants in chronic liver disease and hepatocellular carcinoma
β Scribed by Hidetaka Takashima; Tomoki Nakajima; Michihisa Moriguchi; Satoru Sekoguchi; Taichiroh Nishikawa; Tadashi Watanabe; Tatsuo Katagishi; Hiroyuki Kimura; Masahito Minami; Yoshito Itoh; Keizo Kagawa; Takeshi Okanoue
- Book ID
- 111237289
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 915 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0106-9543
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## Abstract Survivin, a member of the inhibitor of apoptosis protein family, is expressed in most human cancers, but undetectable in normal differentiated adult tissue __in vivo__. Because of this cancerβrelated expression, survivin is a promising target for cancer therapy. To determine the express
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