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In vivo evidence that 5-HT2C receptors inhibit 5-HT neuronal activity via a GABAergic mechanism

✍ Scribed by L Boothman; J Raley; F Denk; E Hirani; T Sharp

Book ID
110009323
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
226 KB
Volume
149
Category
Article
ISSN
0007-1188

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## Abstract Recent studies have established the presence of 5‐hydroxytryptamine (5‐HT)~2A~ receptors on glial cells in culture and in the brain in situ. Here we used cultured C6 glioma cells to investigate the possibility that 5‐HT~2A~ receptors on glia regulate glutamate release from the cell. The