✦ LIBER ✦

In vivo evaluation of vaginal films for mucosal delivery of nitric oxide

✍ Scribed by Jin-Wook Yoo; Gayathri Acharya; Chi H. Lee

Book ID: 108070009
Publisher: Elsevier Science
Year: 2009
Tongue: English
Weight: 417 KB
Volume: 30
Category: Article
ISSN: 0142-9612
DOI: 10.1016/j.biomaterials.2009.04.004

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Characterization of nitric oxide-releasi

Characterization of nitric oxide-releasing microparticles for the mucosal delivery

✍ Jin-Wook Yoo; Jae-Suk Lee; Chi H. Lee 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 355 KB

## Abstract For the treatment of female sexual arousal disorder (FSAD), we developed microparticles made of PLGA containing nitric oxide (NO) donor (DETA NONOate) to efficiently deliver NO to vaginal mucosa. The NO‐releasing microparticles were prepared by various emulsion methods. SEM and DSC stud

Evaluation of a delivery system and moni

Evaluation of a delivery system and monitors for ventilator administration of nitric oxide

✍ Young-Kyoo Choi; Hidekazu Yukioka; Tokuhiro Yamada; Masanori Hayashi; Mitsugu Fu 📂 Article 📅 1995 🏛 Springer 🌐 English ⚖ 589 KB

Physicochemical, tissue distribution, an

Physicochemical, tissue distribution, and vasodilation characteristics of nitrosated serum albumin: delivery of nitric oxide in vivo

✍ Hidemasa Katsumi; Makiya Nishikawa; Shen-Feng Ma; Fumiyoshi Yamashita; Mitsuru H 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 143 KB

Conjugates of nitric oxide (NO) to serum albumins are candidates for controlled delivery of NO in vivo, but their physicochemical and tissue distribution characteristics have hardly been examined yet. In this study, to achieve its in vivo delivery, bovine serum albumin (BSA) was reacted with sodium

In vivo evaluation of alginate microsphe

In vivo evaluation of alginate microspheres of carvedilol for nasal delivery

✍ Sanjay B. Patil; Ankur Kaul; Anil Babbar; Rashi Mathur; Anil Mishra; Krutika K. 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 375 KB

## Abstract Mucoadhesive alginate microspheres of carvedilol (CRV) for nasal administration intended to avoid first pass metabolism and to improve bioavailability were prepared and evaluated. The microspheres were prepared by emulsification cross‐linking method. Radiolabeling of CRV and its microsp

Development and in vitro evaluation of a

Development and in vitro evaluation of a mucoadhesive vaginal delivery system for nystatin

✍ Juliane Hombach; Thomas F. Palmberger; Andreas Bernkop-Schnürch 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 276 KB

The purpose of the present study was to design and evaluate a novel vaginal delivery system for nystatin based on mucoadhesive polymers. L-Cysteine and cysteamine, respectively, were covalently attached to poly(acrylic acid), and the two different thiolated polymers were evaluated in vitro regarding

Determination of the Flux Control Coeffi

Determination of the Flux Control Coefficient of Nitric Oxide Synthase for Nitric Oxide Synthesis in Discrete Brain Regionsin vivo

✍ Mark Salter 📂 Article 📅 1996 🏛 Elsevier Science 🌐 English ⚖ 175 KB

The flux control coefficient of nitric oxide synthase (NOS), for the in vivo synthesis of the key biological mediator nitric oxide (NO), was determined in four rat brain regions with varying NOS activities (cerebral cortex, hippocampus, amygdala and cerebellum) using metabolic control theory. Flux c