In vivo evaluation of early disease progression by X-ray phase-contrast imaging in the adjuvant-induced arthritic rat

A new spin on an old model: In vivo eval

A new spin on an old model: In vivo evaluation of disease progression by magnetic resonance imaging with respect to standard inflammatory parameters and histopathology in the adjuvant arthritic rat

✍ Peer B. Jacobson; Sheryl J. Morgan; Denise M. Wilcox; Phong Nguyen; Christine A. 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 994 KB

Objective. To noninvasively examine the pathogenesis of rat adjuvant-induced arthritis (AIA) by magnetic resonance imaging (MRI), and to correlate MRI indices of disease progression with classic inflammatory parameters and histologic evaluation. Methods. AIA was established in male Lewis rats follo