Sustained-release hormonal preparations
Sustained-release hormonal preparations XV: Release of progesterone from cholesterol pellets in vivo
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A. A. Joseph; J. L. Hill; J. Patel; S. Patel; Fred A. Kincl
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Article
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1977
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John Wiley and Sons
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English
β 536 KB
Progesterone-sterol pellets were made that porvided a zero-order release of progesterone for 80 days. 4-(14)C-Progesterone was used to measure the release in vitro and in vivo. The dissolution rate in vitro (distilled water as the desorbing medium) for progesterone-cholesterol (59:41 w/w) and the pr