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In vivo evaluation of a novel pH- and time-based multiunit colonic drug delivery system

โœ Scribed by C. Bott; M. W. Rudolph; A. R. J. Schneider; S. Schirrmacher; B. Skalsky; H.-U. Petereit; P. Langguth; J. B. Dressman; J. Stein


Book ID
108603655
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
140 KB
Volume
20
Category
Article
ISSN
0269-2813

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The aim of this study was to estimate colon-specific drug delivery of a novel capsule (CS capsule). Theophylline was used as model drug and little was released from the CS capsules in the release medium mimicking physiological environment of stomach to small intestine. However, 66.7 +/- 8.8% theophy