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In vivo evaluation of [18F]fluoroetanidazole as a new marker for imaging tumour hypoxia with positron emission tomography

✍ Scribed by Barthel, H; Wilson, H; Collingridge, D R; Brown, G; Osman, S; Luthra, S K; Brady, F; Workman, P; Price, P M; Aboagye, E O


Book ID
109998087
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
301 KB
Volume
90
Category
Article
ISSN
0007-0920

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## Abstract We developed a method for evaluating tumor glycolytic rates in vivo with nude mice injected with 2‐[F‐18]fluoro‐2‐deoxy‐d‐glucose (FDG) and a dedicated animal positron emission tomography (PET) scanner. Animals were injected with NR‐6 mouse fibroblast tumor cell lines. When tumors achie