𝔖 Bobbio Scriptorium
✦   LIBER   ✦

In vivo emergence of HIV-1 variants resistant to multiple protease inhibitors

✍ Scribed by Condra, Jon H.; Schleif, William A.; Blahy, Olga M.; Gabryelski, Lori J.; Graham, Donald J.; Quintero, Julio; Rhodes, Audrey; Robbins, Helen L.; Roth, Elizabeth; Shivaprakash, Malathi

Book ID
109791647
Publisher
Nature Publishing Group
Year
1995
Tongue
English
Weight
318 KB
Volume
374
Category
Article
ISSN
0028-0836

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Emergence and genetic evolution of HIV-1
Emergence and genetic evolution of HIV-1 variants with mutations conferring resistance to multiple reverse transcriptase and protease inhibitors
✍ Cabana, Marta; Clotet, Bonaventura; Mart�nez, Miguel-Angel 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 302 KB

The emergence of genotypic resistance in protease and reverse transcriptase (RT) gene regions was longitudinally evaluated in plasma samples from a group of 12 HIV-1-infected patients treated with different combination of antiretroviral therapies and selected on the basis of their clinical failure.

Replicative fitness in vivo of HIV-1 var
Replicative fitness in vivo of HIV-1 variants with multiple drug resistance-associated mutations
✍ Helen L. Devereux; Vincent C. Emery; Margaret A. Johnson; Clive Loveday 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 142 KB

## Abstract The relative fitness of HIV‐1 viral variants containing a broad range of drug resistance‐associated mutations has been little studied in vivo. Understanding the relative fitness associated with viruses containing mutations may aid future therapeutic management. The aim of this study was

Longitudinal use of phenotypic resistanc
Longitudinal use of phenotypic resistance testing to HIV-1 protease inhibitors in patients developing HAART failure
✍ Jean Servais; Jean-Marc Plesséria; Christine Lambert; Elodie Fontaine; Isabelle 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 90 KB

## Abstract An “in‐house” recombinant virus protease inhibitor susceptibility assay was carried out (median of 3 per patient) retrospectively in 26 patients failing HIV protease inhibitor based therapy at regular intervals to the initiation of the first protease inhibitor. Patients were treated wit

Diverse pattern of protease inhibitor re
Diverse pattern of protease inhibitor resistance mutations in HIV-1 infected patients failing nelfinavir
✍ Veronica Svedhem; A. Lindkvist; T. Bergroth; Lidman Knut; A. Sönnerborg 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 70 KB

## Abstract The aim of the study was to describe the pattern of resistance mutations in human immunodeficiency virus type 1 (HIV‐1) infected patients experiencing their first protease inhibitor (PI) failure on nelfinavir (NFV)‐containing therapy. Earlier PI‐naïve patients (n = 172) with NFV‐contain