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In vivo efficacy of KRP-109, a novel elastase inhibitor, in a murine model of severe pneumococcal pneumonia

✍ Scribed by Koichi Yamada; Katsunori Yanagihara; Nobuko Araki; Yosuke Harada; Yoshitomo Morinaga; Koichi Izumikawa; Hiroshi Kakeya; Yoshihiro Yamamoto; Hiroo Hasegawa; Shigeru Kohno; Shimeru Kamihira

Book ID
116853692
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
883 KB
Volume
24
Category
Article
ISSN
1094-5539

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1H MRI of pneumococcal pneumonia in a mu
1H MRI of pneumococcal pneumonia in a murine model
✍ Pasquina Marzola; Anna Lanzoni; Elena Nicolato; Vincenza Di Modugno; Patrizia Cr πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 343 KB

## Abstract ## Purpose To detect and quantify pulmonary lesions due to pneumococcal pneumonia in a murine model by ^1^H MRI. ## Materials and Methods Pneumonia was induced in mice (__N__ = 5) by intranasal administration of about 1 Γ— 10^6^ colony‐forming units (CFU) of __Streptococcus pneumonie_