In Vivo effects of a mismatched DS-polynucleotide on lung NK cell activity
✍ Scribed by D. Nolibé; M.N. Thang
- Publisher
- Elsevier Science
- Year
- 1985
- Tongue
- English
- Weight
- 86 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0192-0561
No coin nor oath required. For personal study only.
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Intravenous injection of rabbit anti-asialo-GM, serum, M antiserum previously shown to eliminate splenic natural killer (NK) activity in vitro, profoundly depressed NK activity in CBA, DBN2 and BALBIc nu/nu mice. The effect on N K activity was selective, as treatment of mice with anti-asialo-GM, ser
## Abstract The measurement of natural killer (NK) cell activity often is recommended as an endpoint for inclusion in the non‐clinical immunotoxicity evaluation of environmental chemicals and pharmaceuticals. To date, most data on the impact of immunotoxicants on NK cell activity have been obtained