Structure and folding of glucagon-like p
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Xiaoqing Chang; Danielle Keller; Søren Bjørn; Jens J. Led
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Article
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2001
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John Wiley and Sons
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English
⚖ 217 KB
## Abstract The conformational changes of free, monomeric glucagon‐like peptide‐1‐(7–36)‐amide (GLP‐1) in aqueous solution with increasing concentrations of 2,2,2‐trifluoroethanol (TFE) were monitored by NMR spectroscopy. It was found that GLP‐1 gradually assumes a stable, single‐stranded helical s