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In vivo direct gene transfer into articular cartilage by intraarticular injection mediated by HVJ (Sendai virus) and liposomes

โœ Scribed by Tetsuya Tomita; Hideo Hashimoto; Naruya Tomita; Ryuichi Morishita; Seung Bak Lee; Kenji Hayashida; Norimasa Nakamura; Kazuo Yonenobu; Yasufumi Kaneda; Takahiro Ochi

Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
695 KB
Volume
40
Category
Article
ISSN
0004-3591

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Sustained transgene expression in cartil
Sustained transgene expression in cartilage defects in vivo after transplantation of articular chondrocytes modified by lipid-mediated gene transfer in a gel suspension delivery system
โœ Henning Madry; Magali Cucchiarini; Ute Stein; Klaus Remberger; Michael D. Menger ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 277 KB

## Abstract ## Background Genetically modified chondrocytes may be able to modulate articular cartilage repair. To date, transplantation of modified chondrocytes into cartilage defects has been restricted to viral vectors. We tested the hypothesis that a recombinant gene can be delivered to sites