In vivo determination of body iron stores by natural-abundance deuterium magnetic resonance spectroscopy
β Scribed by Michael G. Irving; Ian M. Brereton; James Field; David M. Doddrell
- Publisher
- John Wiley and Sons
- Year
- 1987
- Tongue
- English
- Weight
- 239 KB
- Volume
- 4
- Category
- Article
- ISSN
- 0740-3194
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β¦ Synopsis
Induction of iron overload in mice using 1% (w/w) dietary carbonyl iron resulted in marked decreases in 'H and 31P NMR relaxation times. Natural-abundance deuterium ('H) NMR spectroscopy has been used to measure ' H TI values in vivo in the presence of body paramagnetic iron. This procedure offers a method for noninvasive determination of body iron stores.
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## Abstract Naturalβabundance ^13^C magnetic resonance spectroscopy was used for determining noninvasively the relative concentration of monoβ and polyunsaturated fatty acids of adipose tissue in two groups of volunteers. The first consisted of subjects who had followed a fatβreduced diet for at le