✦ LIBER ✦
In vivo detection and treatment of ischemia-induced cardiac apoptosis using an MRI-detectable molecular probe and an alpha-adrenergic receptor agonist
✍ Scribed by Justin Lam; Ildiko Toma; Yongquan Gong; Paul C Simpson; Robert C Robbins; Phillip C Yang; Rajesh Dash
- Publisher
- BioMed Central
- Year
- 2012
- Tongue
- English
- Weight
- 186 KB
- Volume
- 14
- Category
- Article
- ISSN
- 1097-6647
No coin nor oath required. For personal study only.
✦ Synopsis
A novel anti-apoptotic alpha-adrenergic agonist preserves left ventricular ejection fraction in mice following myocardial infarction. This therapeutic effect is able to be detected and quantified non-invasively, using T2* signal loss assessment of an Annexin-SPIO molecular apoptosis probe.