Serum from 7 patients who had acute-phase Guillain-Barre syndrome with high anti-peripheral nerve myelin antibody activity (54 to 210 units/ml) was compared with serum from 3 patients in the recovery phase (0 to 17 unitsiml) and serum from 7 disease control subjects (0 to 24 unidml) and 7 normal con
In vivo demyelinating activity of sera from patients with Guillain-Barré syndrome
✍ Scribed by Dr. Takahiko Saida; Kyoko Saida; Robert P. Lisak; Mark J. Brown; Donald H. Silberberg; Arthur K. Asbury
- Publisher
- John Wiley and Sons
- Year
- 1982
- Tongue
- English
- Weight
- 909 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0364-5134
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Among eight sural nerve biopsies from patients with the Guillain-Bar& syndrome (GBS), demyelination was ob- served in five and endoneural mononuclear cell infiltrates in three. Receptors for the activated third component of complement (C3b) were detected within the nerve fascicles. The receptor acti
Serum from 20 patients with Guillain-Barr6 syndrome (GBS), 10 healthy controls and 10 patients with recent cytomegalovirus, Epstein-Barr virus, or Campylobacter jejunilcoli infections was injected into rat sciatic nerve. The 20 GBS patients consisted of 2 groups of 10 patients with different electro