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In vivo Bladder selectivity of darifenacin, a new M3 antimuscarinic agent, in the anesthetised dog

✍ Scribed by Paul Gupta; Charles Anderson; Anthony Carter; James Casey; Donald Newgreen


Book ID
118643886
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
173 KB
Volume
1
Category
Article
ISSN
1569-9056

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The effects of HB 699, a non-sulphonyl urea acyl-amino-alcyl benzoic acid derivative, were studied in unanesthetized dogs. Changes in blood glucose and plasma insulin, glucagon, pancreatic polypeptide and somatostatin were measured after a single intravenous injection. HB 699 caused hypoglycaemia an