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In vivo biodistribution of [N-11C-methyl]KF 17837 using 3-D-PET: Evaluation as a ligand for the study of adenosine A2A receptors

✍ Scribed by Sharon Stone-Elander; Jan-Olov Thorell; Lars Eriksson; Bertil B. Fredholm; Martin Ingvar


Book ID
117688129
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
577 KB
Volume
24
Category
Article
ISSN
0969-8051

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## Abstract A convenient synthesis of [N‐methyl‐^11^C]‐3‐[(6‐dimethylamino)pyridin‐3‐yl]‐2,5‐dimethyl‐__N__,__N__‐dipropylpyrazolo[1,5‐a]pyrimidine‐7‐amine (R121920), a highly selective CRF~1~ antagonist has been developed as a potential PET ligand. 3 ‐ [(6 ‐ methylamino)pyridin ‐ 3 ‐ yl]‐2,5‐dimet