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In Vivo Antitumor Activity of 9-[(2-Phosphonylmethoxy)ethyl]-guanine and Related Phosphonate Nucleotide Analogues

✍ Scribed by Rose, W. C.; Crosswell, A. R.; Bronson, J. J.; Martin, J. C.


Book ID
121402079
Publisher
Oxford University Press
Year
1990
Tongue
English
Weight
305 KB
Volume
82
Category
Article
ISSN
0027-8874

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## Abstract The acidity constants of the twofold protonated acyclic 9‐(5‐phosphonopentyl)adenine, H~2~(dPEEA)^±^, as well as the stability constants of the M(H;dPEEA)^+^ and M(dPEEA) complexes with the metal ions M^2+^ = Mg^2+^, Ca^2+^, Sr^2+^, Ba^2+^, Mn^2+^, Co^2+^, Ni^2+^, Cu^2+^, Zn^2+^ or Cd^2