✦ LIBER ✦

In-vivo and in-vitro dextromethorphan metabolism in SD and DA rat: An animal model of the debrisoquine-type polymorphic oxidation in man

✍ Scribed by Thomas Zysset; Tanja Zeugin; Adrian Küpfer

Book ID: 115780325
Publisher: Elsevier Science
Year: 1988
Tongue: English
Weight: 708 KB
Volume: 37
Category: Article
ISSN: 0006-2952
DOI: 10.1016/0006-2952(88)90314-0

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Differential effect of biliary and micro

Differential effect of biliary and micronodular cirrhosis on oxidative drug metabolism: In vivo-in vitro correlations of dextromethorphan metabolism in rat models

✍ Franz J. Roos; Thomas Zysset; Jürg Reichen 📂 Article 📅 1991 🏛 Elsevier Science 🌐 English ⚖ 551 KB

In vitro topical application and in vivo

In vitro topical application and in vivo pharmacodynamic evaluation of nonivamide hydrogels using Wistar rat as an animal model

✍ Jia-You Fang; Yann-Lii Leu; Ying-Yue Wang; Yi-Hung Tsai 📂 Article 📅 2002 🏛 Elsevier Science 🌐 English ⚖ 185 KB

Biomimetic in vitro oxidation of lapacho

Biomimetic in vitro oxidation of lapachol: A model to predict and analyse the in vivo phase I metabolism of bioactive compounds

✍ Niehues, Michael; Barros, Valéria Priscila; Emery, Flávio da Silva; Dias-Baruffi 📂 Article 📅 2012 🏛 Elsevier Science 🌐 French ⚖ 560 KB

The effect of respiratory and metabolic

The effect of respiratory and metabolic acid-base changes on ionized calcium concentration: in vivo and in vitro experiments in man and rat

✍ HANS OBERLEITHNER; RAINER GREGER; FLORIAN LANG 📂 Article 📅 1982 🏛 John Wiley and Sons 🌐 English ⚖ 456 KB

In vivo and in vitro evidence of altered

In vivo and in vitro evidence of altered nitric oxide metabolism in the spontaneously diabetic, insulin-dependent BB/Edinburgh rat

✍ R. Mark Lindsey; Rosemary S. Peet; Gavin S. Wilkie; Sharon P. Rossiter; William 📂 Article 📅 1997 🏛 Nature Publishing Group 🌐 English ⚖ 562 KB

Pharmacokinetics and metabolism of metop

Pharmacokinetics and metabolism of metoprolol and propranolol in the female DA and female Wistar rat: The female DA rat is not always an animal model for poor metabolizers of CYP2D6

✍ Hiroshi Komura; Masahiro Iwaki 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 228 KB

The purpose of this study was to clarify the pharmacokinetics of CYP2D6 substrates in female DA and Wistar rats, which are regarded as animal models of poor metabolizers and extensive metabolizers, respectively. In vivo pharmacokinetic and in vitro metabolic studies were conducted using metoprolol a