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In vivo activity of CRISPR-mediated virus defence in a hyperthermophilic archaeon

✍ Scribed by Andrea Manica; Ziga Zebec; Daniela Teichmann; Christa Schleper

Book ID
110836903
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
643 KB
Volume
80
Category
Article
ISSN
0950-382X

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## Abstract Sublethally irradiated BALB/c mice innoculated with Moloney sarcoma virus (MSV‐M) develop progressively growing tumors and die within 30 days of virus innoculation. These animals can be protected from tumor progression (and death) by innoculation of small numbers of MSV‐immune T lymphoc