In vivo 300 MHz longitudinally detected ESR-CT imaging in the head of a rat treated with a nitroxide radical
โ Scribed by Yokoyama, H
- Book ID
- 104390916
- Publisher
- Springer
- Year
- 1998
- Tongue
- English
- Weight
- 359 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0968-5243
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โฆ Synopsis
In vivo longitudinally detected ESR (LODESR)-CT system operating at 300 MHz was developed, based on the combination of a bridged loop-gap resonator and a pair of saddle-type pickup coils (STPCs). The sensitivity distribution of the STPCs was simulated on the basis of a magnetic dipole model. A LODESR-CT image of a phantom (a physiological saline solution of a nitroxide radical) was satisfactorily corrected by using the simulation result. LODESR-CT images of the head of a rats, in which nitroxide radical was injected intraperitonally, were also obtained through the correction in the same manner. This is the first in vivo CT (i.e. three-dimensional imaging) study with a 300 MHz ESR.
๐ SIMILAR VOLUMES
A signal detector of longitudinally detected ESR (LODESR) is independent of the resonant frequency. We developed an in vivo LODESR spectrometer operating in the regions of 300, 700, and 900 MHz. Using this apparatus, we estimated signal intensities at different operating frequencies obtained from no