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In vivo 300 MHz longitudinally detected ESR-CT imaging in the head of a rat treated with a nitroxide radical

โœ Scribed by Yokoyama, H


Book ID
104390916
Publisher
Springer
Year
1998
Tongue
English
Weight
359 KB
Volume
7
Category
Article
ISSN
0968-5243

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โœฆ Synopsis


In vivo longitudinally detected ESR (LODESR)-CT system operating at 300 MHz was developed, based on the combination of a bridged loop-gap resonator and a pair of saddle-type pickup coils (STPCs). The sensitivity distribution of the STPCs was simulated on the basis of a magnetic dipole model. A LODESR-CT image of a phantom (a physiological saline solution of a nitroxide radical) was satisfactorily corrected by using the simulation result. LODESR-CT images of the head of a rats, in which nitroxide radical was injected intraperitonally, were also obtained through the correction in the same manner. This is the first in vivo CT (i.e. three-dimensional imaging) study with a 300 MHz ESR.


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In VivoLongitudinally Detected ESR Measu
โœ Hidekatsu Yokoyama; Toshiyuki Sato; Tateaki Ogata; Hiroaki Ohya-Nishiguchi; Hito ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 145 KB

A signal detector of longitudinally detected ESR (LODESR) is independent of the resonant frequency. We developed an in vivo LODESR spectrometer operating in the regions of 300, 700, and 900 MHz. Using this apparatus, we estimated signal intensities at different operating frequencies obtained from no