## Abstract Osteoclasts are specialized macrophage derivatives that secrete acid and proteinases to mobilize bone for mineral homeostasis, growth, and replacement or repair. Osteoclast differentiation generally requires the monocyte growth factor mβCSF and the TNFβfamily cytokine RANKL, although di
In vitrostudy of the role of lenticular epithelial calcium channels and aquaporins in the development of cataract
β Scribed by V. A. Sumerkina; G. K. Popov; L. V. Voronova
- Publisher
- Springer US
- Year
- 2008
- Tongue
- English
- Weight
- 352 KB
- Volume
- 145
- Category
- Article
- ISSN
- 0007-4888
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Aquaporins are a family of water channels considered to play an important role in fluid transport across plasma membranes. Among the reported isoforms, relatively little is known about the functional role of aquaporin 8 (AQP8), and there are no cell lines known to express the AQP8 protein. We report
Of the estimated 35-40 million blindness worldwide, 17 million is caused by cataract and this proportion will double by year 2025. In Africa alone, it is estimated that there are about 3 million cataract blind. As life expectancy in Africa increases so will the incidence of cataract blindness. Exist