✦ LIBER ✦

In VitroSelection for Different Mutational Patterns in the HIV-1 Reverse Transcriptase Using High and Low Selective Pressure of the Nonnucleoside Reverse Transcriptase Inhibitor HBY 097

✍ Scribed by Jörg-Peter Kleim; Irvin Winkler; Manfred Rösner; Reinhard Kirsch; Helga Rübsamen-Waigmann; Arno Paessens; Günther Riess

Book ID: 112271541
Publisher: Elsevier Science
Year: 1997
Tongue: English
Weight: 89 KB
Volume: 231
Category: Article
ISSN: 0042-6822
DOI: 10.1006/viro.1997.8513

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Mutation patterns of the reverse transcr

Mutation patterns of the reverse transcriptase genes in HIV-1 infected patients receiving combinations of nucleoside and non nucleoside inhibitors

✍ Maria Carla Re; I. Bon; P. Monari; M. Borderi; D. Gibellini; P. Schiavone; F. Vi 📂 Article 📅 2003 🏛 Elsevier Science 🌐 English ⚖ 294 KB

Selective Pressure of a Quinoxaline Nonn

Selective Pressure of a Quinoxaline Nonnucleoside Inhibitor of Human Immunodeficiency Virus Type 1 (HIV-1) Reverse Transcriptase (RT) on HIV-1 Replication Results in the Emergence of Nucleoside RT-Inhibitor-Specific (RT Leu-74 → Val or Ile and Val-75 → Leu or Ile) HIV-1 mutants

✍ Jörg-Peter Kleim, Manfred Rösner, Irvin Winkler, Arno Paessens, Reinhard Kirsch, 📂 Article 📅 1996 🏛 National Academy of Sciences 🌐 English ⚖ 346 KB

Structural mechanisms of drug resistance

Structural mechanisms of drug resistance for mutations at codons 181 and 188 in HIV-1 reverse transcriptase and the improved resilience of second generation non-nucleoside inhibitors

✍ J Ren; C Nichols; L Bird; P Chamberlain; K Weaver; S Short; D.I Stuart; D.K Stam 📂 Article 📅 2001 🏛 Elsevier Science 🌐 English ⚖ 680 KB

Prevalence of the mutational pattern E44

Prevalence of the mutational pattern E44D/A and/or V118I in the reverse transcriptase (RT) gene of HIV-1 in relation to treatment with nucleoside analogue RT inhibitors

✍ Brigitte Montes; Michel Segondy 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 93 KB

## Abstract It has been reported that a new pattern of mutations, E44D/A and/or V118I, in the reverse transcriptase (RT) gene of HIV‐1 confers a moderate level of resistance to lamivudine in the absence of the M184V mutation. The prevalence of this mutational pattern was studied in HIV‐1 isolates o

In Search of High Stereocontrol for the

In Search of High Stereocontrol for the Construction of cis-Disubstituted Cyclopropane Compounds. Total Synthesis of a Cyclopropane-Configured Urea-PETT Analogue that Is a HIV-1 Reverse Transcriptase Inhibitor.

✍ Wenhao Hu; Daren J. Timmons; Michael P. Doyle 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 28 KB

Risk factors and occurrence of rash in H

Risk factors and occurrence of rash in HIV-positive patients not receiving nonnucleoside reverse transcriptase inhibitor: data from a randomized study evaluating use of protease inhibitors in nucleoside-experienced patients with very low CD4 levels (<50 cells/mμL)

✍ M Floridia; R Bucciardini; V Fragola; CM Galluzzo; G Giannini; MF Pirillo; R Ami 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 121 KB