✦ LIBER ✦

In VitroMechanisms of Lovastatin on Lung Cancer Cell Lines as a Potential Chemopreventive Agent

✍ Scribed by Elena Maksimova; Ting-An Yie; William N. Rom

Publisher: Springer
Year: 2007
Tongue: English
Weight: 547 KB
Volume: 186
Category: Article
ISSN: 0341-2040
DOI: 10.1007/s00408-007-9053-7

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

The potential of sphingomyelin as a chem

The potential of sphingomyelin as a chemopreventive agent in AOM-induced colon cancer model: wild-type and p53+/– mice

✍ Ying Hu; Richard K. Le Leu; Damien Belobrajdic; Graeme P. Young 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 399 KB

## Abstract A protective effect of sphingolipids on colorectal cancer (CRC) has been reported in certain mouse strains. It is unknown if sphingolipids are protective in a __p53__ deficiency mouse model of CRC. This study investigated the effect of sphingomyelin (SM) on intestinal sphingomyelinase (

DT-diaphorase as a determinant of sensit

DT-diaphorase as a determinant of sensitivity to adriamycin in non-small-cell lung-cancer cell lines

✍ Kazuo Kasahara; Kazuhiko Shibata; Takuma Bando; Yuka Numata; Masaki Fujimura; Ta 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 French ⚖ 510 KB

We have reported the establishment of a mitomycin-C (MMC)resistant non-small-cell lung-cancer cell line, PC-9/MC4. As determined by an MlT assay, this resistant cell line was found to be 4 times more sensitive to adriamycin (ADM) than was the parental PC-9. There were no significant differences in s

Cell death induced byN-methyl-N-nitrosou

Cell death induced byN-methyl-N-nitrosourea, a model SN1 methylating agent, in two lung cancer cell lines of human origin

✍ Angeliki Koryllou; Meropi Patrinou-Georgoula; Constantinos Troungos; Vassiliki P 📂 Article 📅 2009 🏛 Springer 🌐 English ⚖ 489 KB

Effects of gemcitabine on cell prolifera

Effects of gemcitabine on cell proliferation and apoptosis in non-small-cell lung cancer (NSCLC) cell lines

✍ E. Pace; M. Melis; L. Siena; F. Bucchieri; A. M. Vignola; M. Profita; M. Gjomark 📂 Article 📅 2000 🏛 Springer 🌐 English ⚖ 337 KB

Potential role of bcl-2 as a suppressor

Potential role of bcl-2 as a suppressor of tumour angiogenesis in non-small-cell lung cancer

✍ Michael I. Koukourakis; Alexandra Giatromanolaki; Kenneth J. O'Byrne; Ruth M. Wh 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 French ⚖ 231 KB 👁 2 views

It has been reported that genes regulating apoptosis may play a role in tumoral angiogenesis. This study examined the relationship between tumour vascularization, a measure of tumour angiogenesis, and bcl-2 and p53 expression in operable non-small-cell lung cancer (NSCLC). The relationship between b

Identification of 2,3,6-trisubstituted q

Identification of 2,3,6-trisubstituted quinoxaline derivatives as a Wnt2/β-catenin pathway inhibitor in non-small-cell lung cancer cell lines

✍ Sang-Bum Lee; Young In Park; Mi-Sook Dong; Young-Dae Gong 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 784 KB

We screened 1434 small heterocyclic molecules and identified thirteen 2,3,6-trisubstituted quinoxaline derivatives that were able to inhibit the Wnt/b-catenin signal pathway and cell proliferation. In the screen, some of the hit compounds such as the ethylene group-coupled quinoxaline derivatives we