Biliary excretion and pharmacokinetics o
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Gabriele Schuhmann-Giampieri; Heribert Schitt-Willich; Thomas Frenzel
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Article
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1993
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John Wiley and Sons
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English
⚖ 735 KB
The introduction of a lipophilic moiety into the gadolinium chelate Gd-DTPA (dimeglumine gadopentetate, Magnevist) yielded Gd-EOB-DTPA (short form), which has potential as a magnetic resonance contrast agent for liver mass screening. The pharmacokinetics of Gd-EOB-DTPA in rats is nonlinear because a