In vitrochemosensitivity test of human brain tumors using a three-dimensional organ culture with a collagen gel matrix

Increased drug resistance of cultured hu

Increased drug resistance of cultured human cancer cell lines in three-dimensional cellular growth assay using collagen gel matrix

✍ Toshiharu Furukawa; Tetsuro Kubota; Masahiko Watanabe; Suguru Kase; Yoshiro Saik 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 869 KB

## Abstract We have conducted a three‐dimensional cellular growth assay using collagen gel matrix with an endpoint of the 3‐(4,5‐dimethylthiazol‐2‐yl)‐2,5‐diphenyl‐2H tetrazolium bromide (MTT) assay, on four human gastric and colonic cancer cell lines. Three‐dimensionally growing cells in collagen