In VitroandIn VivoInvestigation of Drug-
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Fu-Ying Lee; Dave W. Chen; Chih-Chien Hu; Yu-Te Hsieh; Shih-Jung Liu; Err-Cheng
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Article
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2011
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Springer US
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English
โ 310 KB
This paper developed solvent-free drug-eluting implants for metronidazole delivery for the treatment of periodontal disease and investigated the characteristics of the drug's release from the implants, both in vitro and in vivo, using an HPLC assay. The metronidazole exhibited a two-stage release be