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In vitro synthesis and oligomerization of the mechanosensitive channel of large conductance, MscL, into a functional ion channel

โœ Scribed by Claire E. Price; Armagan Kocer; Stefan Kol; Jan Pieter van der Berg; Arnold J.M. Driessen


Book ID
113622345
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
529 KB
Volume
585
Category
Article
ISSN
0014-5793

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โœ Irene Iscla; Robin Wray; Paul Blount ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› Cold Spring Harbor Laboratory Press ๐ŸŒ English โš– 294 KB

## Abstract The mechanosensitive channel of large conductance (MscL) from __E. coli__ serves as an emergency release valve allowing the cell to survive acute osmotic downshock. It is one of the best studied mechanosensitive channels and serves as a paradigm for how a protein can sense and respond t