Teratogenic effects of bis-diamine on ea
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Nishijima, Setsuko ;Nakagawa, Masao ;Fujino, Hidetoshi ;Hanato, Takashi ;Okamoto
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Article
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2000
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John Wiley and Sons
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English
β 449 KB
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Background: Bis-diamine induces cardiac defects, including conotruncal anomalies in rat embryos when the agent is administered to the mother. To evaluate the teratogenic effects and mechanism of bis-diamine, we performed morphological and immunohistochemical analyses of early rat embryos cultured in