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In vitro studies on enhancing effect of sodium glycocholate on transbuccal permeation of morphine hydrochloride

✍ Scribed by S Şenel; D Duchêne; A.A Hıncal; Y Çapan; G Ponchel

Book ID
118564428
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
431 KB
Volume
51
Category
Article
ISSN
0168-3659

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It was the aim of this study to investigate the permeation enhancing effect of thiolated polycarbophil on the cornea of rabbits in vitro. The proposed reaction mechanism involves the opening of the tight junctions in the corneal epithelium. The modification of polycarbophil was achieved via covalent