In vitro stimulation of rat liver cells by homologous partial hepatectomy serum
โ Scribed by Lynne P. Rutzky; William G. Taylor; Robert W. Pumper
- Book ID
- 112798908
- Publisher
- Society for In Vitro Biology
- Year
- 1971
- Tongue
- English
- Weight
- 346 KB
- Volume
- 7
- Category
- Article
- ISSN
- 1475-2689
No coin nor oath required. For personal study only.
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When epidermal growth factor was given to rats after partial hepatectomy, hepatic putrescine content was significantly increased at 4, 6 and 10 hr compared with control rats. Ornithine decarboxylase activity was also increased. Hepatic ornithine decarboxylase messenger RNA content was significantly
## Abstract Partial hepatectomy in the rat stimulated the phosphorylation of three proteins (Mr 100,000, 48,000, and 35,000) in the plasma membranes of the proliferatively activated cells of the liver remnant. The autophosphorylation of these plasma membrane proteins began to rise about 8 hours aft