In vitro stimulation of monocyte tissue factor activity by autologous platelets
โ Scribed by Patricia B. Pinder; Jane A. Hunt; Leo R. Zacharski
- Publisher
- John Wiley and Sons
- Year
- 1985
- Tongue
- English
- Weight
- 617 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0361-8609
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HIV-1 Tat protein has been shown to induce chemotaxis and recruitment of monocytes. In the present study, we evaluated whether HIV-1 Tat protein was able to induce the synthesis of platelet-activating factor (PAF), which is a potent mediator of cell motility, and whether the synthesis of PAF was ins
Expression of the gene for tissue factor, the cell-surface initiator of blood coagulation, was examined by stimulating growth-arrested human fibroblasts with serum and measuring changes in the cellular content of tissue factor mRNA, antigen, and activity. Maximum tissue factor mRNA levels were reach