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In vitro specificities of Arabidopsis co-activator histone acetyltransferases: implications for histone hyperacetylation in gene activation

✍ Scribed by Keith W. Earley; Molly S. Shook; Brent Brower-Toland; Leslie Hicks; Craig S. Pikaard

Book ID
110867767
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
649 KB
Volume
52
Category
Article
ISSN
0960-7412

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Polyamines stimulate expression of a variety of genes, including many implicated in cell proliferation. Indeed, aberrant expression of ornithine decarboxylase (ODC), a rate-limiting enzyme in polyamine biosynthesis, plays a causal role in tumorigenesis. Gene activity is influenced by dynamic changes