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In vitro replication and mutagenesis of a novel reversion vector with selective DNA damage in the supF gene

โœ Scribed by Nicole M King; Michael P Carty; Kathleen Dixon


Book ID
114070333
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
128 KB
Volume
476
Category
Article
ISSN
0027-5107

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## Abstract Gene amplification plays a pivotal role in human malignancy. Highly amplified genes frequently localize to extrachromosomal double minutes (dmin), which usually segregate to daughter cells in association with mitotic chromosomes. We and others had shown that treatment with lowโ€dose hydr