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In vitro pore-forming activity of the lantibiotic nisin : Role of protonmotive force and lipid composition

✍ Scribed by Maria J. García GARCERÁ; Marieke G. L. ELFERINK; Arnold J. M. DRIESSEN; Wil N. KONINGS


Book ID
115129886
Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
624 KB
Volume
212
Category
Article
ISSN
1432-1327

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✍ Anderluh, Gregor; Lakey, Jeremy 📂 Article 📅 2010 🏛 Springer New York 🌐 English ⚖ 664 KB

Formation of transmembrane pores is a very effective way of killing cells. It is thus not surprising that many bacterial and eukaryotic toxic agents are pore-forming proteins. Pore formation in a target membrane is a complex process composed of several steps; proteins need to attach to the lipid mem