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In VITRO Polarized TH17 Cells Induce Severe Acute Graft-Versus-Host Disease

โœ Scribed by C. Iclozan; C. Liu; Y. Yu; T. Yi; C. Anasetti; X.-Z. Yu


Book ID
116280872
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
65 KB
Volume
15
Category
Article
ISSN
1083-8791

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โ€œAbout 25 years ago, Mosmann & Coffman introduced the TH1 / TH2 paradigm of T helper cell differentiation which helped explain many aspects of adaptive immunity from eliminating intracellular versus extracellular pathogens to induction of different types of tissue inflammation. However, TH1 / TH2 pa