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In vitro phosphorylation and the identification of multiple protein changes in membranes of Chinese hamster lung cells resistant to adriamycin

✍ Scribed by Wallace Marsh; Melvin S. Center


Book ID
115778155
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
602 KB
Volume
34
Category
Article
ISSN
0006-2952

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## Abstract Prolonged hypoxia induced transient drug resistance in Chinese hamster lung fibroblasts. Previously hypoxic cells were resistant to adriamycin and resistant to etoposide. Complete recovery of etoposide sensitivity was observed following re‐aeration for 24 hr. A change in P‐glycoprotein