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In-vitro mutagenic potential and effect on permeability of co-administered drugs across Caco-2 cell monolayers of Rubus idaeus and its fortified fractions

✍ Scribed by Kari Kreander; Anna Galkin; Satu Vuorela; Päivi Tammela; Leena Laitinen; Marina Heinonen; Pia Vuorela


Book ID
111770473
Publisher
Pharmaceutical Press
Year
2006
Tongue
English
Weight
297 KB
Volume
58
Category
Article
ISSN
2042-7158

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## Abstract Metabolism by phase II enzymes and transport from intestinal cells back into the lumen by ATP binding cassette (ABC) transporters limits the bioavailability of the flavanone hesperetin, the aglycone of hesperidin. This study investigates to what extent other flavonoids modulate the meta