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In vitro model systems of carcinogenesis: Interaction between c-Ha-ras oncogene and immortalized cells

✍ Scribed by L. Z. Topol'; D. D. Spitkovskii; F. L. Kiselev


Book ID
104964611
Publisher
Springer US
Year
1988
Tongue
English
Weight
891 KB
Volume
105
Category
Article
ISSN
0007-4888

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## Abstract BALB/c 3T3 cells were exposed to 7, 12‐dimethylbenz[__a__]anthracene (DMBA) and resultant transformed foci were analyzed for the presence of A^182^ → T mutation at codon 61 of Ha‐__ras__ (a mutation found in many DMBA‐induced animal tumors). None of the 30 independently cloned transform