In vitro metabolism of a novel phosphodiesterase-5 inhibitor DA-8159 in rat liver preparations using liquid chromatography/electrospray mass spectrometry

In vitro metabolism of a new H+/K+ ATPas

In vitro metabolism of a new H+/K+ ATPase inhibitor DBM-819 in liver microsomes using HPLC and electrospray mass spectrometry

✍ Sung Jin Choi; Hye-Young Ji; Hee-Yong Lee; Dong Ha Lee; Hong Lim; Hye Suk Lee 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 103 KB 👁 3 views

## Abstract The metabolism of 1‐(2‐methyl‐4‐methoxyphenyl)‐4‐[(3‐hydroxypropyl)amino]‐6‐methyl‐2,3‐dihydropyrrolo[3,2c]quinoline (DBM‐819), a new H^+^/K^+^ ATPase inhibitor, has been studied by HPLC with spectrometric detection and on‐line LC‐electrospray mass spectrometry. __In vitro__ incubation