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In vitro metabolism and bioactivation of 1,2,3-trichloropropane

✍ Scribed by Gregory L. Weber; I.Glenn Sipes

Book ID
113207733
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
787 KB
Volume
113
Category
Article
ISSN
0041-008X

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✍ Wiersma, David A. ;Schnellmann, Rick G. ;Sipes, I. Glenn πŸ“‚ Article πŸ“… 1986 πŸ› John Wiley and Sons 🌐 English βš– 610 KB

The nematocide, grain fumigant, and gasoline additive 1,2-dibromoethane (DBE) is both a cellular and a genetic toxin that is metabolically activated in rats and mice by mixed function oxidases (MFO) as well as glutathione S-transferases (GST). The purpose of this study was to determine whether DBE i