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In vitro mesenchymal stem cells differentiation into hepatocyte-like cells in the presence and absence of 3D microenvironment

✍ Scribed by El-Hamid, Samah Abd; Mogawer, Ahmed

Book ID: 120634833
Publisher: Springer-Verlag
Year: 2013
Tongue: English
Weight: 497 KB
Volume: 23
Category: Article
ISSN: 1618-5641
DOI: 10.1007/s00580-013-1741-5

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## Abstract Differentiation of stem cells is tightly regulated by the microenvironment which is mainly composed of nonparenchymal cells. Herein, we investigated effect of hepatic stellate cells (HSCs) in different states on mesenchymal stem cells (MSCs) differentiation. Rat HSCs were isolated and s