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In-vitro maintenance and functionality of primary renal tubules and their application in the study of relative renal toxicity of nephrotoxic drugs

✍ Scribed by Xu, Jinsheng; Patton, David; Jackson, Simon K.; Purcell, Wendy M.


Book ID
121795648
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
878 KB
Volume
68
Category
Article
ISSN
1056-8719

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## Abstract Rat primary renal cortical tubular cells were exposed to seven test substances, some with, and some without, known direct renal tubular cell toxicity. Cells were exposed to the substances at either one‐third or one‐tenth of the TC~50~ for cytotoxicity for 6 h or 24 h, so as not to induc