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In vitro isolation and characterization of a human rhinovirus variant resistant to a 3C protease inhibitor

✍ Scribed by S. Binford; C. Ford; S. Fuhrman; S.E. Webber; K. Okano; A.K. Patick

Book ID
114145130
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
92 KB
Volume
34
Category
Article
ISSN
0166-3542

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T47D human breast cancer cells were grown in I pM benzo[a]pyrene (BaP) for 3.5 months, and 2 BaP-resistant (BaPR) variant cell lines (C5 and CIO) were isolated. Decreased aryl hydrocarbon (Ah)-responsiveness in the C5 and C I0 BaPR cells was characterized by lower (80 to 9ovo) induction of CYP I A l