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In vitro inhibitory effect of rupatadine on histamine and TNF-α release from dispersed canine skin mast cells and the human mast cell line HMC-1

✍ Scribed by M. Queralt, P. Brazís, M. Merlos, F. de Mora, A. Puigdemont

Book ID
113011124
Publisher
SP Birkhäuser Verlag Basel
Year
2000
Tongue
English
Weight
113 KB
Volume
49
Category
Article
ISSN
1420-908X

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✍ Mireia Queralt; Pilar Brazís; Manuel Merlos; Anna Puigdemont 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 142 KB

The present studies were performed to compare the cutaneous antiallergic effects of rupatadine, a new potent dual antagonist of histamine and platelet-activating factor (PAF), with those of loratadine (an H 1 -antihistamine) and SR-27417A (a PAF antagonist). Two experimental models were used: an in