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In vitro inhibition of aromatase by the enantiomers of aminoglutethimide and analogs

✍ Scribed by Dr. Patrick O.J. Ogbunude; Hassan Y. Aboul-Enein

Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
378 KB
Volume
6
Category
Article
ISSN
0899-0042

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## Abstract Bisphosphonates are analogues of pyrophosphate, a key physicochemical inhibitor of mineralisation. We examined the direct actions of bisphosphonates on the function of cultured osteoblasts derived from rat calvariae. Treatment with zoledronate, the most potent bisphosphonate studied, re