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In vitro — in vivo correlation of the mechanism and rate of placental transfer of anti-HIV dideoxynucleoside drugs

Book ID
117315184
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
70 KB
Volume
16
Category
Article
ISSN
0143-4004

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The Ex Vivo human placental transfer of the anti-HIV nucleoside inhibitor abacavir and the protease inhibitor amprenavir
✍ R.E. Bawdon 📂 Article 📅 1998 🏛 Hindawi Publishing Corporation 🌐 English ⚖ 52 KB 👁 2 views

## Objective: The transfer of abacavir, a new nucleoside inhibitor, and amprenavir, a new protease inhibitor, used for the treatment of human immunodeficiency virus, has been studied in the ex vivo human placental model. ## Methods: The ex vivo human placental model used c14 antipyrine to determi