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In vitro generation of germ cells from murine embryonic stem cells

✍ Scribed by West, Jason A; Park, In-Hyun; Daley, George Q; Geijsen, Niels

Book ID
109945923
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
339 KB
Volume
1
Category
Article
ISSN
1750-2799

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Mice chimeric for embryonic stem (ES) cells have not always successfully produced ES-derived offspring. Here we show that the male gametes from ES cells could be selected in male chimeric mice testes by labeling donor ES cells or host blastocytes with GFP. Male GFP-expressing ES-derived germ cells o