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In-vitro fertilization and culture of mouse embryos in vitro significantly retards the onset of insulin-like growth factor-II expression from the zygotic genome

โœ Scribed by Stojanov, T.


Book ID
125467809
Publisher
Oxford University Press
Year
1999
Tongue
English
Weight
270 KB
Volume
5
Category
Article
ISSN
1360-9947

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The mannose 6-phosphate/insulin-like growth factor-II receptor (M6P/IGF-IIR) is thought to act as a suppressor of tumor growth by binding the mitogenic peptide IGF-II and modulating its extracellular levels via degradation. This receptor has been found to be absent or nonfunctional in a high proport